Span, who originally tweaked his neck during outfield practice before Saturday's game, saw a chiropractor on Monday to get his neck adjusted.
He took batting practice before Tuesday's game against the Blue Jays and reported no problems. He was also on the list to travel to Wednesday's game against the Phillies in Clearwater, Fla.
"I feel a lot better compared to the way I felt two days ago," Span said. "My range of motion is a lot better. Hopefully soon I'll be back out there."
Span, who maintains the injury isn't related to the concussion-like symptoms that bothered him last season, is batting .385 with a .467 on-base percentage in five games this spring.
Joining Span on the trip to Clearwater is shortstop Tsuyoshi Nishioka, who missed the last two games with a sprained left pinkie. He's expected to start at shortstop.
Infielder Steve Pearce will miss the trip, however, as he exited Tuesday's game with a strained right calf and is day to day.