Instead, his two primary options -- Yuniesky Betancourt and Alex Gonzalez -- were needed to start at third base and first on Friday. Ramirez, the regular third baseman, is on the disabled list with a sprained left knee, and first baseman Corey Hart is still recovering from right knee surgery.
Weeks, meanwhile, has been swinging though a prolonged slump. Through Wednesday, he had five hits in his last 59 at-bats.
Roenicke said he hadn't approached Weeks in recent days about taking a break, and dismissed the notion that Weeks' two-error night in San Diego on Wednesday was a sign of taking an offensive funk into the field.
"Oh, no," Roenicke said. "That's a one-game thing, where any player can have a bad day, offensively or defensively. Certainly, defensively, it's going to come up. He has been playing well for us.
"It's like when you see a guy like [defensive-minded catcher Martin] Maldonado having a bad game throwing for us last year. That's the last thing I think he would have problems with, but it's going to happen."
Roenicke saw positives at the plate in Weeks' 1-for-4 night against the Padres on Wednesday. His last at-bat, for example, was a line drive to the left-center-field gap that the Padres had well-positioned.
"I thought he had pretty good at-bats," Roenicke said. "To me, it's a positive. I know the numbers don't always show that, but I thought it was a good day for him. When you keep squaring-up balls, it's going to happen. You can't keep lining out. You can't keep running into bad luck all the time."
Adam McCalvy is a reporter for MLB.com. Read his blog, Brew Beat, and follow him on Twitter at @AdamMcCalvy. This story was not subject to the approval of Major League Baseball or its clubs.