Instead, Garza will pitch the Game 3 against the Braves next Wednesday at Miller Park. Marco Estrada will work the Fenway Park opener, followed by Wily Peralta in the fifth game of the season.
"We're trying to put the three guys up front and just go more times with them," manager Ron Roenicke said. "The thing is, we have room that if we want to change it, we still can change it. If something comes up, we can still realign the three, four and five pitchers. I want to keep options open."
After Estrada and Peralta pitch the first two games in Boston, Gallardo will come back for the finale. Lohse would then start the Phillies' home opener April 7.
Adam McCalvy is a reporter for MLB.com. Read his blog, Brew Beat, and follow him on Twitter at @AdamMcCalvy. This story was not subject to the approval of Major League Baseball or its clubs.