First-base umpire Jeff Nelson called Carpenter safe, with John Jay coming around to score from second as Gorzelanny protested the call.
Roenicke challenged and the call was overturned after a 1-minute, 25-second review, ending the inning and negating the run.
It was the 14th challenge this season by the Brewers, who have won eight.
Jim Hoehm is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.